Feldene
Brand names,
Feldene
Analogs
Feldene
Brand Names Mixture
- Skin Shield Liquid Bandage (Alcohol Anhydrous + Benzethonium Chloride + Dyclonine Hydrochloride)
- Tanac Medicated Gel (Allantoin + Dyclonine Hydrochloride)
Feldene
Chemical_Formula
C27H36O8
Feldene
RX_link
http://www.rxlist.com/cgi/generic2/prednicarbate.htm
Feldene
fda sheet
Feldene
msds (material safety sheet)
Feldene
Synthesis Reference
No information avaliable
Feldene
Molecular Weight
488.57 g/mol
Feldene
Melting Point
No information avaliable
Feldene
H2O Solubility
No information avaliable
Feldene
State
No information avaliable
Feldene
LogP
3.392
Feldene
Dosage Forms
Cream; Ointment
Feldene
Indication
For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Feldene
Pharmacology
Corticosteroids diffuse across cell membranes and complex with specific cytoplasmic receptors. These complexes then enter the cell nucleus, bind to DNA (chromatin), and stimulate transcription of messenger RNA (mRNA) and subsequent protein synthesis of various inhibitory enzymes responsible for the anti-inflammatory effects of topical corticosteroids. These anti-inflammatory effects include inhibition of early processes such as edema, fibrin deposition, capillary dilatation, movement of phagocytes into the area, and phagocytic activities. Later processes, such as capillary production, collagen deposition, and keloid formation also are inhibited by corticosteroids.
Feldene
Absorption
Absorbed systemically across the stratum corneum.
Feldene
side effects and Toxicity
No information avaliable
Feldene
Patient Information
No information avaliable
Feldene
Organisms Affected
Humans and other mammals