Geldene
Brand names,
Geldene
Analogs
Geldene
Brand Names Mixture
- Skin Shield Liquid Bandage (Alcohol Anhydrous + Benzethonium Chloride + Dyclonine Hydrochloride)
- Tanac Medicated Gel (Allantoin + Dyclonine Hydrochloride)
Geldene
Chemical_Formula
C27H36O8
Geldene
RX_link
http://www.rxlist.com/cgi/generic2/prednicarbate.htm
Geldene
fda sheet
Geldene
msds (material safety sheet)
Geldene
Synthesis Reference
No information avaliable
Geldene
Molecular Weight
488.57 g/mol
Geldene
Melting Point
No information avaliable
Geldene
H2O Solubility
No information avaliable
Geldene
State
No information avaliable
Geldene
LogP
3.392
Geldene
Dosage Forms
Cream; Ointment
Geldene
Indication
For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Geldene
Pharmacology
Corticosteroids diffuse across cell membranes and complex with specific cytoplasmic receptors. These complexes then enter the cell nucleus, bind to DNA (chromatin), and stimulate transcription of messenger RNA (mRNA) and subsequent protein synthesis of various inhibitory enzymes responsible for the anti-inflammatory effects of topical corticosteroids. These anti-inflammatory effects include inhibition of early processes such as edema, fibrin deposition, capillary dilatation, movement of phagocytes into the area, and phagocytic activities. Later processes, such as capillary production, collagen deposition, and keloid formation also are inhibited by corticosteroids.
Geldene
Absorption
Absorbed systemically across the stratum corneum.
Geldene
side effects and Toxicity
No information avaliable
Geldene
Patient Information
No information avaliable
Geldene
Organisms Affected
Humans and other mammals