Pirkam
Brand names,
Pirkam
Analogs
Pirkam
Brand Names Mixture
- Skin Shield Liquid Bandage (Alcohol Anhydrous + Benzethonium Chloride + Dyclonine Hydrochloride)
- Tanac Medicated Gel (Allantoin + Dyclonine Hydrochloride)
Pirkam
Chemical_Formula
C27H36O8
Pirkam
RX_link
http://www.rxlist.com/cgi/generic2/prednicarbate.htm
Pirkam
fda sheet
Pirkam
msds (material safety sheet)
Pirkam
Synthesis Reference
No information avaliable
Pirkam
Molecular Weight
488.57 g/mol
Pirkam
Melting Point
No information avaliable
Pirkam
H2O Solubility
No information avaliable
Pirkam
State
No information avaliable
Pirkam
LogP
3.392
Pirkam
Dosage Forms
Cream; Ointment
Pirkam
Indication
For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Pirkam
Pharmacology
Corticosteroids diffuse across cell membranes and complex with specific cytoplasmic receptors. These complexes then enter the cell nucleus, bind to DNA (chromatin), and stimulate transcription of messenger RNA (mRNA) and subsequent protein synthesis of various inhibitory enzymes responsible for the anti-inflammatory effects of topical corticosteroids. These anti-inflammatory effects include inhibition of early processes such as edema, fibrin deposition, capillary dilatation, movement of phagocytes into the area, and phagocytic activities. Later processes, such as capillary production, collagen deposition, and keloid formation also are inhibited by corticosteroids.
Pirkam
Absorption
Absorbed systemically across the stratum corneum.
Pirkam
side effects and Toxicity
No information avaliable
Pirkam
Patient Information
No information avaliable
Pirkam
Organisms Affected
Humans and other mammals