Ropinirole en es it fr

Ropinirole Brand names, Ropinirole Analogs

Ropinirole Brand Names Mixture

  • No information avaliable

Ropinirole Chemical_Formula


Ropinirole RX_link

Ropinirole fda sheet

Ropinirole FDA

Ropinirole msds (material safety sheet)

Ropinirole MSDS

Ropinirole Synthesis Reference

No information avaliable

Ropinirole Molecular Weight

260.375 g/mol

Ropinirole Melting Point

243-250 oC

Ropinirole H2O Solubility

133 mg/mL

Ropinirole State


Ropinirole LogP


Ropinirole Dosage Forms

Tablet (0.25 mg, 0.5 mg, 1 mg, 2 mg, 4 mg or 5 mg)

Ropinirole Indication

For the treatment of the signs and symptoms of idiopathic Parkinson's disease. Also used for the treatment of restless legs syndrome.

Ropinirole Pharmacology

Ropinirole is a nonergot dopamine agonist with high relative in vitro specificity and full intrinsic activity at the D2 subfamily of dopamine receptors, binding with higher affinity to D3 than to D2 or D4 receptor subtypes. The relevance of D3 receptor binding in Parkinson's disease is unknown. The mechanism of ropinirole-induced postural hypotension is presumed to be due to a D2 -mediated blunting of the noradrenergic response to standing and subsequent decrease in peripheral vascular resistance.

Ropinirole Absorption

Absolute bioavailability is 55%, indicating a first pass effect. Food does not affect the extent of absorption.

Ropinirole side effects and Toxicity

Symptoms of overdose include agitation, chest pain, confusion, drowsiness, facial muscle movements, grogginess, increased jerkiness of movement, symptoms of low blood pressure (dizziness, light-headedness)upon standing, nausea, and vomiting.

Ropinirole Patient Information

No information avaliable

Ropinirole Organisms Affected

Humans and other mammals