Ropinirolum [INN-Latin] en es it fr

Ropinirolum [INN-Latin] Brand names, Ropinirolum [INN-Latin] Analogs

Ropinirolum [INN-Latin] Brand Names Mixture

  • No information avaliable

Ropinirolum [INN-Latin] Chemical_Formula


Ropinirolum [INN-Latin] RX_link

Ropinirolum [INN-Latin] fda sheet

Ropinirolum_[INN-Latin] FDA

Ropinirolum [INN-Latin] msds (material safety sheet)

Ropinirolum_[INN-Latin] MSDS

Ropinirolum [INN-Latin] Synthesis Reference

No information avaliable

Ropinirolum [INN-Latin] Molecular Weight

260.375 g/mol

Ropinirolum [INN-Latin] Melting Point

243-250 oC

Ropinirolum [INN-Latin] H2O Solubility

133 mg/mL

Ropinirolum [INN-Latin] State


Ropinirolum [INN-Latin] LogP


Ropinirolum [INN-Latin] Dosage Forms

Tablet (0.25 mg, 0.5 mg, 1 mg, 2 mg, 4 mg or 5 mg)

Ropinirolum [INN-Latin] Indication

For the treatment of the signs and symptoms of idiopathic Parkinson's disease. Also used for the treatment of restless legs syndrome.

Ropinirolum [INN-Latin] Pharmacology

Ropinirole is a nonergot dopamine agonist with high relative in vitro specificity and full intrinsic activity at the D2 subfamily of dopamine receptors, binding with higher affinity to D3 than to D2 or D4 receptor subtypes. The relevance of D3 receptor binding in Parkinson's disease is unknown. The mechanism of ropinirole-induced postural hypotension is presumed to be due to a D2 -mediated blunting of the noradrenergic response to standing and subsequent decrease in peripheral vascular resistance.

Ropinirolum [INN-Latin] Absorption

Absolute bioavailability is 55%, indicating a first pass effect. Food does not affect the extent of absorption.

Ropinirolum [INN-Latin] side effects and Toxicity

Symptoms of overdose include agitation, chest pain, confusion, drowsiness, facial muscle movements, grogginess, increased jerkiness of movement, symptoms of low blood pressure (dizziness, light-headedness)upon standing, nausea, and vomiting.

Ropinirolum [INN-Latin] Patient Information

No information avaliable

Ropinirolum [INN-Latin] Organisms Affected

Humans and other mammals