Rastinon
Rastinon Brand names, Rastinon Analogs
- Aglicid
- Apo-Tolbutamide
- Arkozal
- Artosin
- Artozin
- Butamid
- Butamide
- Diaben
- Diabetamid
- Diabetol
- Diabuton
- Diasulfon
- Dirastan
- Dolipol
- Drabet
- Glyconon
- Ipoglicone
- Mobenol
- Novo-Butamide
- Orabet
- Oralin
- Orezan
- Orinase
- Orinase Diagnostic
- Orinaz
- Oterben
- Pramidex
- Rastinon
- Restinon
- Sk-tolbutamide
- Tol-Tab
- Tolbusal
- Tolbutamid
- Toluina
- Tolumid
- Toluvan
- Tolylsulfonylbutylurea
- Willbutamide
Rastinon Brand Names Mixture
- No information avaliable
Rastinon Chemical_Formula
C12H18N2O3S
Rastinon RX_link
No information avaliable
Rastinon fda sheet
Rastinon msds (material safety sheet)
Rastinon Synthesis Reference
No information avaliable
Rastinon Molecular Weight
270.349 g/mol
Rastinon Melting Point
128.5 oC
Rastinon H2O Solubility
109 mg/L
Rastinon State
Solid
Rastinon LogP
2.765
Rastinon Dosage Forms
Tablet (250 and 500 mg)
Rastinon Indication
Used as an oral hypoglycemic agent in non-insulin-dependent (type 2) Diabetes Miletus with adult onset.
Rastinon Pharmacology
Tolbutamide, a second-generation sulfonylurea antidiabetic agent, is used with diet to lower blood glucose levels in patients with diabetes mellitus type II. Tolbutamide is twice as potent as the related second-generation agent glipizide. Tolbutamide lowers blood sugar by stimulating the pancreas to secrete insulin and helping the body use insulin efficiently. The pancreas must be able to produce insulin for this drug to work.
Rastinon Absorption
Well absorbed. Absorption is unaltered if taken with food but is increased with high pH.
Rastinon side effects and Toxicity
Oral, mouse: LD50 = 2600 mg/kg
Rastinon Patient Information
Treatment with tolbutamide may increase the risk of death from cardiovascular disease compared to treatment of diabetes with diet alone or diet plus insulin. Discuss with your doctor the risks and benefits of treatment with tolbutamide. Know the signs and symptoms of low blood sugar (hypoglycemia), which include headache, drowsiness, weakness, dizziness, fast heartbeat, sweating, tremor, and nausea. Carry a piece of hard candy or glucose tablets with you to treat episodes of low blood sugar. Follow your diet, medication, and exercise routines closely. Changing any of them can affect blood sugar levels. Do not change your dose of tolbutamide without first talking to your doctor. Avoid alcohol. It lowers blood sugar and may interfere with your diabetes treatment.
Rastinon Organisms Affected
Humans and other mammals
