Quetiapine
Quetiapine Brand names, Quetiapine Analogs
Quetiapine Brand Names Mixture
- No information avaliable
Quetiapine Chemical_Formula
C21H25N3O2S
Quetiapine RX_link
http://www.rxlist.com/cgi/generic2/quetiap.htm
Quetiapine fda sheet
Quetiapine msds (material safety sheet)
Quetiapine Synthesis Reference
No information avaliable
Quetiapine Molecular Weight
383.508 g/mol
Quetiapine Melting Point
No information avaliable
Quetiapine H2O Solubility
Moderate
Quetiapine State
Solid
Quetiapine LogP
2.296
Quetiapine Dosage Forms
Tablet
Quetiapine Indication
For the treatment of schizophrenia and acute manic episodes associated with bipolar I disorder, as either monotherapy or adjunct therapy to lithium or divalproex.
Quetiapine Pharmacology
Quetiapine is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Quetiapine is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), and dopamine type 2 (D2) receptors. Quetiapine is an antagonist at serotonin 5-HT1A and 5HT2, dopamine D1 and D2, histamine H1, and adrenergic alpha 1 and alpha 2 receptors. Quetiapine has no significant affinity for cholinergic muscarinic or benzodiazepine receptors. Drowsiness and orthostatic hypotension associated with use of quetiapine may be explained by its antagonism of histamine H1 and adrenergic alpha 1 receptors, respectively. Quetiapine's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug.
Quetiapine Absorption
Rapidly and well absorbed.
Quetiapine side effects and Toxicity
Symptoms of overdose include drowsiness and sedation, tachycardia, and hypotension.
Quetiapine Patient Information
Quetiapine Organisms Affected
Humans and other mammals
