Seroquel
Seroquel Brand names, Seroquel Analogs
Seroquel Brand Names Mixture
- No information avaliable
Seroquel Chemical_Formula
C21H25N3O2S
Seroquel RX_link
http://www.rxlist.com/cgi/generic2/quetiap.htm
Seroquel fda sheet
Seroquel msds (material safety sheet)
Seroquel Synthesis Reference
No information avaliable
Seroquel Molecular Weight
383.508 g/mol
Seroquel Melting Point
No information avaliable
Seroquel H2O Solubility
Moderate
Seroquel State
Solid
Seroquel LogP
2.296
Seroquel Dosage Forms
Tablet
Seroquel Indication
For the treatment of schizophrenia and acute manic episodes associated with bipolar I disorder, as either monotherapy or adjunct therapy to lithium or divalproex.
Seroquel Pharmacology
Quetiapine is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Quetiapine is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), and dopamine type 2 (D2) receptors. Quetiapine is an antagonist at serotonin 5-HT1A and 5HT2, dopamine D1 and D2, histamine H1, and adrenergic alpha 1 and alpha 2 receptors. Quetiapine has no significant affinity for cholinergic muscarinic or benzodiazepine receptors. Drowsiness and orthostatic hypotension associated with use of quetiapine may be explained by its antagonism of histamine H1 and adrenergic alpha 1 receptors, respectively. Quetiapine's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug.
Seroquel Absorption
Rapidly and well absorbed.
Seroquel side effects and Toxicity
Symptoms of overdose include drowsiness and sedation, tachycardia, and hypotension.
Seroquel Patient Information
Seroquel Organisms Affected
Humans and other mammals
