Quetiapine fumarate
Quetiapine fumarate Brand names, Quetiapine fumarate Analogs
Quetiapine fumarate Brand Names Mixture
- No information avaliable
Quetiapine fumarate Chemical_Formula
C21H25N3O2S
Quetiapine fumarate RX_link
http://www.rxlist.com/cgi/generic2/quetiap.htm
Quetiapine fumarate fda sheet
Quetiapine fumarate msds (material safety sheet)
Quetiapine fumarate Synthesis Reference
No information avaliable
Quetiapine fumarate Molecular Weight
383.508 g/mol
Quetiapine fumarate Melting Point
No information avaliable
Quetiapine fumarate H2O Solubility
Moderate
Quetiapine fumarate State
Solid
Quetiapine fumarate LogP
2.296
Quetiapine fumarate Dosage Forms
Tablet
Quetiapine fumarate Indication
For the treatment of schizophrenia and acute manic episodes associated with bipolar I disorder, as either monotherapy or adjunct therapy to lithium or divalproex.
Quetiapine fumarate Pharmacology
Quetiapine is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Quetiapine is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), and dopamine type 2 (D2) receptors. Quetiapine is an antagonist at serotonin 5-HT1A and 5HT2, dopamine D1 and D2, histamine H1, and adrenergic alpha 1 and alpha 2 receptors. Quetiapine has no significant affinity for cholinergic muscarinic or benzodiazepine receptors. Drowsiness and orthostatic hypotension associated with use of quetiapine may be explained by its antagonism of histamine H1 and adrenergic alpha 1 receptors, respectively. Quetiapine's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug.
Quetiapine fumarate Absorption
Rapidly and well absorbed.
Quetiapine fumarate side effects and Toxicity
Symptoms of overdose include drowsiness and sedation, tachycardia, and hypotension.
Quetiapine fumarate Patient Information
Quetiapine fumarate Organisms Affected
Humans and other mammals
