Quetiapine hemifumarate
Quetiapine hemifumarate Brand names, Quetiapine hemifumarate Analogs
Quetiapine hemifumarate Brand Names Mixture
- No information avaliable
Quetiapine hemifumarate Chemical_Formula
C21H25N3O2S
Quetiapine hemifumarate RX_link
http://www.rxlist.com/cgi/generic2/quetiap.htm
Quetiapine hemifumarate fda sheet
Quetiapine hemifumarate msds (material safety sheet)
Quetiapine hemifumarate Synthesis Reference
No information avaliable
Quetiapine hemifumarate Molecular Weight
383.508 g/mol
Quetiapine hemifumarate Melting Point
No information avaliable
Quetiapine hemifumarate H2O Solubility
Moderate
Quetiapine hemifumarate State
Solid
Quetiapine hemifumarate LogP
2.296
Quetiapine hemifumarate Dosage Forms
Tablet
Quetiapine hemifumarate Indication
For the treatment of schizophrenia and acute manic episodes associated with bipolar I disorder, as either monotherapy or adjunct therapy to lithium or divalproex.
Quetiapine hemifumarate Pharmacology
Quetiapine is a psychotropic agent belonging to the chemical class of benzisoxazole derivatives and is indicated for the treatment of schizophrenia. Quetiapine is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), and dopamine type 2 (D2) receptors. Quetiapine is an antagonist at serotonin 5-HT1A and 5HT2, dopamine D1 and D2, histamine H1, and adrenergic alpha 1 and alpha 2 receptors. Quetiapine has no significant affinity for cholinergic muscarinic or benzodiazepine receptors. Drowsiness and orthostatic hypotension associated with use of quetiapine may be explained by its antagonism of histamine H1 and adrenergic alpha 1 receptors, respectively. Quetiapine's antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug.
Quetiapine hemifumarate Absorption
Rapidly and well absorbed.
Quetiapine hemifumarate side effects and Toxicity
Symptoms of overdose include drowsiness and sedation, tachycardia, and hypotension.
Quetiapine hemifumarate Patient Information
Quetiapine hemifumarate Organisms Affected
Humans and other mammals
