Porfimer
Brand names,
Porfimer
Analogs
Porfimer
Brand Names Mixture
Porfimer
Chemical_Formula
C68H74N8O11
Porfimer
RX_link
http://www.rxlist.com/cgi/generic3/photofrin.htm
Porfimer
fda sheet
Porfimer
msds (material safety sheet)
Porfimer
Synthesis Reference
No information avaliable
Porfimer
Molecular Weight
1179.36 g/mol
Porfimer
Melting Point
No information avaliable
Porfimer
H2O Solubility
No information avaliable
Porfimer
State
Solid
Porfimer
LogP
5.127
Porfimer
Dosage Forms
Powder for solution
Porfimer
Indication
Indicated in the treatment of esophageal cancer.
Porfimer
Pharmacology
Porfimer is a photosensitizing agent used in the photodynamic therapy (PDT) of tumors. Porfimer is indicated for the palliation of patients with completely obstructing esophageal cancer, or of patients with partially obstructing esophageal cancer who cannot be satisfactorily treated with Nd:YAG laser therapy, reduction of obstruction and palliation of symptoms in patients with completely or partially obstructing endobronchial nonsmall cell lung cancer (NSCLC), and the treatment of microinvasive endobronchial NSCLC in patients for whom surgery and radiotherapy are not indicated. The cytotoxic and antitumor actions of porfimer are light and oxygen dependent. Tumor selectivity in treatment occurs through a combination of selective retention of porfimer and selective delivery of light.
Porfimer
Absorption
No information avaliable
Porfimer
side effects and Toxicity
No information avaliable
Porfimer
Patient Information
No information avaliable
Porfimer
Organisms Affected
Humans and other mammals