Dihematoporphyrin ether
Brand names,
Dihematoporphyrin ether
Analogs
Dihematoporphyrin ether
Brand Names Mixture
Dihematoporphyrin ether
Chemical_Formula
C68H74N8O11
Dihematoporphyrin ether
RX_link
http://www.rxlist.com/cgi/generic3/photofrin.htm
Dihematoporphyrin ether
fda sheet
Dihematoporphyrin ether
msds (material safety sheet)
Dihematoporphyrin ether
Synthesis Reference
No information avaliable
Dihematoporphyrin ether
Molecular Weight
1179.36 g/mol
Dihematoporphyrin ether
Melting Point
No information avaliable
Dihematoporphyrin ether
H2O Solubility
No information avaliable
Dihematoporphyrin ether
State
Solid
Dihematoporphyrin ether
LogP
5.127
Dihematoporphyrin ether
Dosage Forms
Powder for solution
Dihematoporphyrin ether
Indication
Indicated in the treatment of esophageal cancer.
Dihematoporphyrin ether
Pharmacology
Porfimer is a photosensitizing agent used in the photodynamic therapy (PDT) of tumors. Porfimer is indicated for the palliation of patients with completely obstructing esophageal cancer, or of patients with partially obstructing esophageal cancer who cannot be satisfactorily treated with Nd:YAG laser therapy, reduction of obstruction and palliation of symptoms in patients with completely or partially obstructing endobronchial nonsmall cell lung cancer (NSCLC), and the treatment of microinvasive endobronchial NSCLC in patients for whom surgery and radiotherapy are not indicated. The cytotoxic and antitumor actions of porfimer are light and oxygen dependent. Tumor selectivity in treatment occurs through a combination of selective retention of porfimer and selective delivery of light.
Dihematoporphyrin ether
Absorption
No information avaliable
Dihematoporphyrin ether
side effects and Toxicity
No information avaliable
Dihematoporphyrin ether
Patient Information
No information avaliable
Dihematoporphyrin ether
Organisms Affected
Humans and other mammals