DHP ether
Brand names,
DHP ether
Analogs
DHP ether
Brand Names Mixture
DHP ether
Chemical_Formula
C68H74N8O11
DHP ether
RX_link
http://www.rxlist.com/cgi/generic3/photofrin.htm
DHP ether
fda sheet
DHP ether
msds (material safety sheet)
DHP ether
Synthesis Reference
No information avaliable
DHP ether
Molecular Weight
1179.36 g/mol
DHP ether
Melting Point
No information avaliable
DHP ether
H2O Solubility
No information avaliable
DHP ether
State
Solid
DHP ether
LogP
5.127
DHP ether
Dosage Forms
Powder for solution
DHP ether
Indication
Indicated in the treatment of esophageal cancer.
DHP ether
Pharmacology
Porfimer is a photosensitizing agent used in the photodynamic therapy (PDT) of tumors. Porfimer is indicated for the palliation of patients with completely obstructing esophageal cancer, or of patients with partially obstructing esophageal cancer who cannot be satisfactorily treated with Nd:YAG laser therapy, reduction of obstruction and palliation of symptoms in patients with completely or partially obstructing endobronchial nonsmall cell lung cancer (NSCLC), and the treatment of microinvasive endobronchial NSCLC in patients for whom surgery and radiotherapy are not indicated. The cytotoxic and antitumor actions of porfimer are light and oxygen dependent. Tumor selectivity in treatment occurs through a combination of selective retention of porfimer and selective delivery of light.
DHP ether
Absorption
No information avaliable
DHP ether
side effects and Toxicity
No information avaliable
DHP ether
Patient Information
No information avaliable
DHP ether
Organisms Affected
Humans and other mammals