Photofrin
Brand names,
Photofrin
Analogs
Photofrin
Brand Names Mixture
Photofrin
Chemical_Formula
C68H74N8O11
Photofrin
RX_link
http://www.rxlist.com/cgi/generic3/photofrin.htm
Photofrin
fda sheet
Photofrin
msds (material safety sheet)
Photofrin
Synthesis Reference
No information avaliable
Photofrin
Molecular Weight
1179.36 g/mol
Photofrin
Melting Point
No information avaliable
Photofrin
H2O Solubility
No information avaliable
Photofrin
State
Solid
Photofrin
LogP
5.127
Photofrin
Dosage Forms
Powder for solution
Photofrin
Indication
Indicated in the treatment of esophageal cancer.
Photofrin
Pharmacology
Porfimer is a photosensitizing agent used in the photodynamic therapy (PDT) of tumors. Porfimer is indicated for the palliation of patients with completely obstructing esophageal cancer, or of patients with partially obstructing esophageal cancer who cannot be satisfactorily treated with Nd:YAG laser therapy, reduction of obstruction and palliation of symptoms in patients with completely or partially obstructing endobronchial nonsmall cell lung cancer (NSCLC), and the treatment of microinvasive endobronchial NSCLC in patients for whom surgery and radiotherapy are not indicated. The cytotoxic and antitumor actions of porfimer are light and oxygen dependent. Tumor selectivity in treatment occurs through a combination of selective retention of porfimer and selective delivery of light.
Photofrin
Absorption
No information avaliable
Photofrin
side effects and Toxicity
No information avaliable
Photofrin
Patient Information
No information avaliable
Photofrin
Organisms Affected
Humans and other mammals