DHE
DHE Brand names, DHE Analogs
DHE Brand Names Mixture
- No information avaliable
DHE Chemical_Formula
C68H74N8O11
DHE RX_link
http://www.rxlist.com/cgi/generic3/photofrin.htm
DHE fda sheet
DHE msds (material safety sheet)
DHE Synthesis Reference
No information avaliable
DHE Molecular Weight
1179.36 g/mol
DHE Melting Point
No information avaliable
DHE H2O Solubility
No information avaliable
DHE State
Solid
DHE LogP
5.127
DHE Dosage Forms
Powder for solution
DHE Indication
Indicated in the treatment of esophageal cancer.
DHE Pharmacology
Porfimer is a photosensitizing agent used in the photodynamic therapy (PDT) of tumors. Porfimer is indicated for the palliation of patients with completely obstructing esophageal cancer, or of patients with partially obstructing esophageal cancer who cannot be satisfactorily treated with Nd:YAG laser therapy, reduction of obstruction and palliation of symptoms in patients with completely or partially obstructing endobronchial nonsmall cell lung cancer (NSCLC), and the treatment of microinvasive endobronchial NSCLC in patients for whom surgery and radiotherapy are not indicated. The cytotoxic and antitumor actions of porfimer are light and oxygen dependent. Tumor selectivity in treatment occurs through a combination of selective retention of porfimer and selective delivery of light.
DHE Absorption
No information avaliable
DHE side effects and Toxicity
No information avaliable
DHE Patient Information
No information avaliable
DHE Organisms Affected
Humans and other mammals
