Pilocarpine monohydrochloride en es it fr

Pilocarpine monohydrochloride Brand names, Pilocarpine monohydrochloride Analogs

Pilocarpine monohydrochloride Brand Names Mixture

  • E-Pilo 1 Ophthalmic Solution (Epinephrine bitartrate + Pilocarpine hydrochloride)
  • E-Pilo 2 Ophthalmic Solution (Epinephrine bitartrate + Pilocarpine hydrochloride)
  • E-Pilo 4 Ophthalmic Solution (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • E-Pilo 6 Ophthalmic Solution (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • E-Pilo-1 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • E-Pilo-2 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • E-Pilo-4 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • E-Pilo-6 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • Timpilo 2 (Pilocarpine Hydrochloride + Timolol Maleate)
  • Timpilo 4 (Pilocarpine Hydrochloride + Timolol Maleate)

Pilocarpine monohydrochloride Chemical_Formula


Pilocarpine monohydrochloride RX_link


Pilocarpine monohydrochloride fda sheet

Pilocarpine_monohydrochloride FDA

Pilocarpine monohydrochloride msds (material safety sheet)

Pilocarpine_monohydrochloride MSDS

Pilocarpine monohydrochloride Synthesis Reference

Preobrashenski et al., Ber. 66, 1187 (1933)

Pilocarpine monohydrochloride Molecular Weight

208.257 g/mol

Pilocarpine monohydrochloride Melting Point

34 oC

Pilocarpine monohydrochloride H2O Solubility

1000 mg/ml

Pilocarpine monohydrochloride State


Pilocarpine monohydrochloride LogP


Pilocarpine monohydrochloride Dosage Forms

Drops; Gel; Implant; Liquid; Solution

Pilocarpine monohydrochloride Indication

For the treatment of radiation-induced dry mouth (xerostomia) and symptoms of dry mouth in patients with Sjögrens syndrome.

Pilocarpine monohydrochloride Pharmacology

Pilocarpine is a choline ester miotic and a positively charged quaternary ammonium compound. Pilocarpine, in appropriate dosage, can increase secretion by the exocrine glands. The sweat, salivary, lacrimal, gastric, pancreatic, and intestinal glands and the mucous cells of the respiratory tract may be stimulated. When applied topically to the eye as a single dose it causes miosis, spasm of accommodation, and may cause a transitory rise in intraocular pressure followed by a more persistent fall. Dose-related smooth muscle stimulation of the intestinal tract may cause increased tone, increased motility, spasm, and tenesmus. Bronchial smooth muscle tone may increase. The tone and motility of urinary tract, gallbladder, and biliary duct smooth muscle may be enhanced. Pilocarpine may have paradoxical effects on the cardiovascular system. The expected effect of a muscarinic agonist is vasodepression, but administration of pilocarpine may produce hypertension after a brief episode of hypotension. Bradycardia and tachycardia have both been reported with use of pilocarpine.

Pilocarpine monohydrochloride Absorption

There was a decrease in the rate of absorption of pilocarpine from SALAGEN Tablets when taken with a high fat meal by 12 healthy male volunteers

Pilocarpine monohydrochloride side effects and Toxicity

No information avaliable

Pilocarpine monohydrochloride Patient Information

Patients should be informed that pilocarpine may cause visual disturbances, especially at night, that could impair their ability to drive safely.

If a patient sweats excessively while taking pilocarpine hydrochloride and cannot drink enough liquid, the patient should consult a physician. Dehydration may develop.

Pilocarpine monohydrochloride Organisms Affected

Humans and other mammals