PharmacyCodes



Minims Pilocarpine en es it fr

Minims Pilocarpine Brand names, Minims Pilocarpine Analogs

Minims Pilocarpine Brand Names Mixture

  • E-Pilo 1 Ophthalmic Solution (Epinephrine bitartrate + Pilocarpine hydrochloride)
  • E-Pilo 2 Ophthalmic Solution (Epinephrine bitartrate + Pilocarpine hydrochloride)
  • E-Pilo 4 Ophthalmic Solution (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • E-Pilo 6 Ophthalmic Solution (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • E-Pilo-1 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • E-Pilo-2 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • E-Pilo-4 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • E-Pilo-6 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • Timpilo 2 (Pilocarpine Hydrochloride + Timolol Maleate)
  • Timpilo 4 (Pilocarpine Hydrochloride + Timolol Maleate)

Minims Pilocarpine Chemical_Formula

C11H16N2O2

Minims Pilocarpine RX_link

http://www.rxlist.com/cgi/generic3/salagen.htm

Minims Pilocarpine fda sheet

Minims_Pilocarpine FDA

Minims Pilocarpine msds (material safety sheet)

Minims_Pilocarpine MSDS

Minims Pilocarpine Synthesis Reference

Preobrashenski et al., Ber. 66, 1187 (1933)

Minims Pilocarpine Molecular Weight

208.257 g/mol

Minims Pilocarpine Melting Point

34 oC

Minims Pilocarpine H2O Solubility

1000 mg/ml

Minims Pilocarpine State

Solid

Minims Pilocarpine LogP

1.02

Minims Pilocarpine Dosage Forms

Drops; Gel; Implant; Liquid; Solution

Minims Pilocarpine Indication

For the treatment of radiation-induced dry mouth (xerostomia) and symptoms of dry mouth in patients with Sjögrens syndrome.

Minims Pilocarpine Pharmacology

Pilocarpine is a choline ester miotic and a positively charged quaternary ammonium compound. Pilocarpine, in appropriate dosage, can increase secretion by the exocrine glands. The sweat, salivary, lacrimal, gastric, pancreatic, and intestinal glands and the mucous cells of the respiratory tract may be stimulated. When applied topically to the eye as a single dose it causes miosis, spasm of accommodation, and may cause a transitory rise in intraocular pressure followed by a more persistent fall. Dose-related smooth muscle stimulation of the intestinal tract may cause increased tone, increased motility, spasm, and tenesmus. Bronchial smooth muscle tone may increase. The tone and motility of urinary tract, gallbladder, and biliary duct smooth muscle may be enhanced. Pilocarpine may have paradoxical effects on the cardiovascular system. The expected effect of a muscarinic agonist is vasodepression, but administration of pilocarpine may produce hypertension after a brief episode of hypotension. Bradycardia and tachycardia have both been reported with use of pilocarpine.

Minims Pilocarpine Absorption

There was a decrease in the rate of absorption of pilocarpine from SALAGEN Tablets when taken with a high fat meal by 12 healthy male volunteers

Minims Pilocarpine side effects and Toxicity

No information avaliable

Minims Pilocarpine Patient Information

Patients should be informed that pilocarpine may cause visual disturbances, especially at night, that could impair their ability to drive safely.

If a patient sweats excessively while taking pilocarpine hydrochloride and cannot drink enough liquid, the patient should consult a physician. Dehydration may develop.

Minims Pilocarpine Organisms Affected

Humans and other mammals