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Pilocarpine hydrochloride en es it fr

Pilocarpine hydrochloride Brand names, Pilocarpine hydrochloride Analogs

Pilocarpine hydrochloride Brand Names Mixture

  • E-Pilo 1 Ophthalmic Solution (Epinephrine bitartrate + Pilocarpine hydrochloride)
  • E-Pilo 2 Ophthalmic Solution (Epinephrine bitartrate + Pilocarpine hydrochloride)
  • E-Pilo 4 Ophthalmic Solution (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • E-Pilo 6 Ophthalmic Solution (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • E-Pilo-1 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • E-Pilo-2 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • E-Pilo-4 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • E-Pilo-6 Oph Soln (Epinephrine Bitartrate + Pilocarpine Hydrochloride)
  • Timpilo 2 (Pilocarpine Hydrochloride + Timolol Maleate)
  • Timpilo 4 (Pilocarpine Hydrochloride + Timolol Maleate)

Pilocarpine hydrochloride Chemical_Formula

C11H16N2O2

Pilocarpine hydrochloride RX_link

http://www.rxlist.com/cgi/generic3/salagen.htm

Pilocarpine hydrochloride fda sheet

Pilocarpine_hydrochloride FDA

Pilocarpine hydrochloride msds (material safety sheet)

Pilocarpine_hydrochloride MSDS

Pilocarpine hydrochloride Synthesis Reference

Preobrashenski et al., Ber. 66, 1187 (1933)

Pilocarpine hydrochloride Molecular Weight

208.257 g/mol

Pilocarpine hydrochloride Melting Point

34 oC

Pilocarpine hydrochloride H2O Solubility

1000 mg/ml

Pilocarpine hydrochloride State

Solid

Pilocarpine hydrochloride LogP

1.02

Pilocarpine hydrochloride Dosage Forms

Drops; Gel; Implant; Liquid; Solution

Pilocarpine hydrochloride Indication

For the treatment of radiation-induced dry mouth (xerostomia) and symptoms of dry mouth in patients with Sjögrens syndrome.

Pilocarpine hydrochloride Pharmacology

Pilocarpine is a choline ester miotic and a positively charged quaternary ammonium compound. Pilocarpine, in appropriate dosage, can increase secretion by the exocrine glands. The sweat, salivary, lacrimal, gastric, pancreatic, and intestinal glands and the mucous cells of the respiratory tract may be stimulated. When applied topically to the eye as a single dose it causes miosis, spasm of accommodation, and may cause a transitory rise in intraocular pressure followed by a more persistent fall. Dose-related smooth muscle stimulation of the intestinal tract may cause increased tone, increased motility, spasm, and tenesmus. Bronchial smooth muscle tone may increase. The tone and motility of urinary tract, gallbladder, and biliary duct smooth muscle may be enhanced. Pilocarpine may have paradoxical effects on the cardiovascular system. The expected effect of a muscarinic agonist is vasodepression, but administration of pilocarpine may produce hypertension after a brief episode of hypotension. Bradycardia and tachycardia have both been reported with use of pilocarpine.

Pilocarpine hydrochloride Absorption

There was a decrease in the rate of absorption of pilocarpine from SALAGEN Tablets when taken with a high fat meal by 12 healthy male volunteers

Pilocarpine hydrochloride side effects and Toxicity

No information avaliable

Pilocarpine hydrochloride Patient Information

Patients should be informed that pilocarpine may cause visual disturbances, especially at night, that could impair their ability to drive safely.

If a patient sweats excessively while taking pilocarpine hydrochloride and cannot drink enough liquid, the patient should consult a physician. Dehydration may develop.

Pilocarpine hydrochloride Organisms Affected

Humans and other mammals