Pefloxacin
Pefloxacin Brand names, Pefloxacin Analogs
Pefloxacin Brand Names Mixture
- No information avaliable
Pefloxacin Chemical_Formula
C17H20FN3O3
Pefloxacin RX_link
No information avaliable
Pefloxacin fda sheet
Pefloxacin msds (material safety sheet)
Pefloxacin Synthesis Reference
No information avaliable
Pefloxacin Molecular Weight
333.358 g/mol
Pefloxacin Melting Point
271 oC
Pefloxacin H2O Solubility
11.4 mg/mL at 25 oC
Pefloxacin State
Solid
Pefloxacin LogP
1.49
Pefloxacin Dosage Forms
No information avaliable
Pefloxacin Indication
For the treatment of uncomplicated gonococcal urethritis in males and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract.
Pefloxacin Pharmacology
Pefloxacin is a fluoroquinolone antibiotic. Flouroquinolones such as pefloxacin possess excellent activity against gram-negative aerobic bacteria such as E.coli and Neisseria gonorrhoea as well as gram-positive bacteria including S. pneumoniae and Staphylococcus aureus. They also posses effective activity against shigella, salmonella, campylobacter, gonococcal organisms, and multi drug resistant pseudomonas and enterobacter.
Pefloxacin Absorption
Well absorbed by the oral route.
Pefloxacin side effects and Toxicity
Adverse reactions include peripheral neuropathy, nervousness, agitation, anxiety, and phototoxic events (rash, itching, burning) due to sunlight exposure.
Pefloxacin Patient Information
No information avaliable
Pefloxacin Organisms Affected
Enteric bacteria and other eubacteria
