Pefloxacine
Pefloxacine Brand names, Pefloxacine Analogs
Pefloxacine Brand Names Mixture
- No information avaliable
Pefloxacine Chemical_Formula
C17H20FN3O3
Pefloxacine RX_link
No information avaliable
Pefloxacine fda sheet
Pefloxacine msds (material safety sheet)
Pefloxacine Synthesis Reference
No information avaliable
Pefloxacine Molecular Weight
333.358 g/mol
Pefloxacine Melting Point
271 oC
Pefloxacine H2O Solubility
11.4 mg/mL at 25 oC
Pefloxacine State
Solid
Pefloxacine LogP
1.49
Pefloxacine Dosage Forms
No information avaliable
Pefloxacine Indication
For the treatment of uncomplicated gonococcal urethritis in males and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract.
Pefloxacine Pharmacology
Pefloxacin is a fluoroquinolone antibiotic. Flouroquinolones such as pefloxacin possess excellent activity against gram-negative aerobic bacteria such as E.coli and Neisseria gonorrhoea as well as gram-positive bacteria including S. pneumoniae and Staphylococcus aureus. They also posses effective activity against shigella, salmonella, campylobacter, gonococcal organisms, and multi drug resistant pseudomonas and enterobacter.
Pefloxacine Absorption
Well absorbed by the oral route.
Pefloxacine side effects and Toxicity
Adverse reactions include peripheral neuropathy, nervousness, agitation, anxiety, and phototoxic events (rash, itching, burning) due to sunlight exposure.
Pefloxacine Patient Information
No information avaliable
Pefloxacine Organisms Affected
Enteric bacteria and other eubacteria
