Pefloxacin methanesulfonate
Brand names,
Pefloxacin methanesulfonate
Analogs
Pefloxacin methanesulfonate
Brand Names Mixture
Pefloxacin methanesulfonate
Chemical_Formula
C17H20FN3O3
Pefloxacin methanesulfonate
RX_link
No information avaliable
Pefloxacin methanesulfonate
fda sheet
Pefloxacin methanesulfonate
msds (material safety sheet)
Pefloxacin methanesulfonate
Synthesis Reference
No information avaliable
Pefloxacin methanesulfonate
Molecular Weight
333.358 g/mol
Pefloxacin methanesulfonate
Melting Point
271 oC
Pefloxacin methanesulfonate
H2O Solubility
11.4 mg/mL at 25 oC
Pefloxacin methanesulfonate
State
Solid
Pefloxacin methanesulfonate
LogP
1.49
Pefloxacin methanesulfonate
Dosage Forms
No information avaliable
Pefloxacin methanesulfonate
Indication
For the treatment of uncomplicated gonococcal urethritis in males and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract.
Pefloxacin methanesulfonate
Pharmacology
Pefloxacin is a fluoroquinolone antibiotic. Flouroquinolones such as pefloxacin possess excellent activity against gram-negative aerobic bacteria such as E.coli and Neisseria gonorrhoea as well as gram-positive bacteria including S. pneumoniae and Staphylococcus aureus. They also posses effective activity against shigella, salmonella, campylobacter, gonococcal organisms, and multi drug resistant pseudomonas and enterobacter.
Pefloxacin methanesulfonate
Absorption
Well absorbed by the oral route.
Pefloxacin methanesulfonate
side effects and Toxicity
Adverse reactions include peripheral neuropathy, nervousness, agitation, anxiety, and phototoxic events (rash, itching, burning) due to sunlight exposure.
Pefloxacin methanesulfonate
Patient Information
No information avaliable
Pefloxacin methanesulfonate
Organisms Affected
Enteric bacteria and other eubacteria