PFLX
Brand names,
PFLX
Analogs
PFLX
Brand Names Mixture
PFLX
Chemical_Formula
C17H20FN3O3
PFLX
RX_link
No information avaliable
PFLX
fda sheet
PFLX
msds (material safety sheet)
PFLX
Synthesis Reference
No information avaliable
PFLX
Molecular Weight
333.358 g/mol
PFLX
Melting Point
271 oC
PFLX
H2O Solubility
11.4 mg/mL at 25 oC
PFLX
State
Solid
PFLX
LogP
1.49
PFLX
Dosage Forms
No information avaliable
PFLX
Indication
For the treatment of uncomplicated gonococcal urethritis in males and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract.
PFLX
Pharmacology
Pefloxacin is a fluoroquinolone antibiotic. Flouroquinolones such as pefloxacin possess excellent activity against gram-negative aerobic bacteria such as E.coli and Neisseria gonorrhoea as well as gram-positive bacteria including S. pneumoniae and Staphylococcus aureus. They also posses effective activity against shigella, salmonella, campylobacter, gonococcal organisms, and multi drug resistant pseudomonas and enterobacter.
PFLX
Absorption
Well absorbed by the oral route.
PFLX
side effects and Toxicity
Adverse reactions include peripheral neuropathy, nervousness, agitation, anxiety, and phototoxic events (rash, itching, burning) due to sunlight exposure.
PFLX
Patient Information
No information avaliable
PFLX
Organisms Affected
Enteric bacteria and other eubacteria