Pefloxacin mesylate
Brand names,
Pefloxacin mesylate
Analogs
Pefloxacin mesylate
Brand Names Mixture
Pefloxacin mesylate
Chemical_Formula
C17H20FN3O3
Pefloxacin mesylate
RX_link
No information avaliable
Pefloxacin mesylate
fda sheet
Pefloxacin mesylate
msds (material safety sheet)
Pefloxacin mesylate
Synthesis Reference
No information avaliable
Pefloxacin mesylate
Molecular Weight
333.358 g/mol
Pefloxacin mesylate
Melting Point
271 oC
Pefloxacin mesylate
H2O Solubility
11.4 mg/mL at 25 oC
Pefloxacin mesylate
State
Solid
Pefloxacin mesylate
LogP
1.49
Pefloxacin mesylate
Dosage Forms
No information avaliable
Pefloxacin mesylate
Indication
For the treatment of uncomplicated gonococcal urethritis in males and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract.
Pefloxacin mesylate
Pharmacology
Pefloxacin is a fluoroquinolone antibiotic. Flouroquinolones such as pefloxacin possess excellent activity against gram-negative aerobic bacteria such as E.coli and Neisseria gonorrhoea as well as gram-positive bacteria including S. pneumoniae and Staphylococcus aureus. They also posses effective activity against shigella, salmonella, campylobacter, gonococcal organisms, and multi drug resistant pseudomonas and enterobacter.
Pefloxacin mesylate
Absorption
Well absorbed by the oral route.
Pefloxacin mesylate
side effects and Toxicity
Adverse reactions include peripheral neuropathy, nervousness, agitation, anxiety, and phototoxic events (rash, itching, burning) due to sunlight exposure.
Pefloxacin mesylate
Patient Information
No information avaliable
Pefloxacin mesylate
Organisms Affected
Enteric bacteria and other eubacteria