Oxeze Turbuhaler Foradil
Oxeze Turbuhaler Foradil Brand names, Oxeze Turbuhaler Foradil Analogs
Oxeze Turbuhaler Foradil Brand Names Mixture
- No information avaliable
Oxeze Turbuhaler Foradil Chemical_Formula
C19H24N2O4
Oxeze Turbuhaler Foradil RX_link
http://www.rxlist.com/cgi/generic/foradil.htm
Oxeze Turbuhaler Foradil fda sheet
Oxeze Turbuhaler Foradil msds (material safety sheet)
Oxeze Turbuhaler Foradil Synthesis Reference
No information avaliable
Oxeze Turbuhaler Foradil Molecular Weight
344.405 g/mol
Oxeze Turbuhaler Foradil Melting Point
No information avaliable
Oxeze Turbuhaler Foradil H2O Solubility
Slightly (as fumarate salt)
Oxeze Turbuhaler Foradil State
Solid
Oxeze Turbuhaler Foradil LogP
2.083
Oxeze Turbuhaler Foradil Dosage Forms
Metered-dose (aerosol); Powder
Oxeze Turbuhaler Foradil Indication
For use as long-term maintenance treatment of asthma in patients 6 years of age and older with reversible obstructive airways disease, including patients with symptoms of nocturnal asthma, who are using optimal corticosteroid treatment and experiencing regular or frequent breakthrough symptoms requiring use of a short-acting bronchodilator.
Oxeze Turbuhaler Foradil Pharmacology
Formoterol is a long-acting selective beta2-adrenergic receptor agonist (beta2-agonist). Inhaled formoterol fumarate acts locally in the lung as a bronchodilator. In vitro studies have shown that formoterol has more than 200-fold greater agonist activity at beta2-receptors than at beta1- receptors. Although beta2-receptors are the predominant adrenergic receptors in bronchial smooth muscle and beta1-receptors are the predominant receptors in the heart, there are also beta2-receptors in the human heart comprising 10%-50% of the total beta-adrenergic receptors. The precise function of these receptors has not been established, but they raise the possibility that even highly selective beta2- agonists may have cardiac effects.
Oxeze Turbuhaler Foradil Absorption
Rapidly absorbed into plasma following administration by oral inhalation. It is likely that the majority of the inhaled formoterol delivered is swallowed and then absorbed from the gastrointestinal tract.
Oxeze Turbuhaler Foradil side effects and Toxicity
An overdosage is likely to lead to effects that are typical of ß2-adrenergic stimulants: nausea, vomiting, headache, tremor, somnolence, palpitations, tachycardia, ventricular arrhythmias, metabolic acidosis, hypokalemia, hyperglycemia.
Oxeze Turbuhaler Foradil Patient Information
Oxeze Turbuhaler Foradil Organisms Affected
Humans and other mammals
