Foradil en es it fr

Foradil Brand names, Foradil Analogs

Foradil Brand Names Mixture

  • No information avaliable

Foradil Chemical_Formula

C19H24N2O4

Foradil RX_link

http://www.rxlist.com/cgi/generic/foradil.htm

Foradil fda sheet

Foradil FDA

Foradil msds (material safety sheet)

Foradil MSDS

Foradil Synthesis Reference

No information avaliable

Foradil Molecular Weight

344.405 g/mol

Foradil Melting Point

No information avaliable

Foradil H2O Solubility

Slightly (as fumarate salt)

Foradil State

Solid

Foradil LogP

2.083

Foradil Dosage Forms

Metered-dose (aerosol); Powder

Foradil Indication

For use as long-term maintenance treatment of asthma in patients 6 years of age and older with reversible obstructive airways disease, including patients with symptoms of nocturnal asthma, who are using optimal corticosteroid treatment and experiencing regular or frequent breakthrough symptoms requiring use of a short-acting bronchodilator.

Foradil Pharmacology

Formoterol is a long-acting selective beta2-adrenergic receptor agonist (beta2-agonist). Inhaled formoterol fumarate acts locally in the lung as a bronchodilator. In vitro studies have shown that formoterol has more than 200-fold greater agonist activity at beta2-receptors than at beta1- receptors. Although beta2-receptors are the predominant adrenergic receptors in bronchial smooth muscle and beta1-receptors are the predominant receptors in the heart, there are also beta2-receptors in the human heart comprising 10%-50% of the total beta-adrenergic receptors. The precise function of these receptors has not been established, but they raise the possibility that even highly selective beta2- agonists may have cardiac effects.

Foradil Absorption

Rapidly absorbed into plasma following administration by oral inhalation. It is likely that the majority of the inhaled formoterol delivered is swallowed and then absorbed from the gastrointestinal tract.

Foradil side effects and Toxicity

An overdosage is likely to lead to effects that are typical of ß2-adrenergic stimulants: nausea, vomiting, headache, tremor, somnolence, palpitations, tachycardia, ventricular arrhythmias, metabolic acidosis, hypokalemia, hyperglycemia.

Foradil Patient Information

Foradil Organisms Affected

Humans and other mammals