NovoSeven (Novo Nordisk)
NovoSeven (Novo Nordisk) Brand names, NovoSeven (Novo Nordisk) Analogs
NovoSeven (Novo Nordisk) Brand Names Mixture
- No information avaliable
NovoSeven (Novo Nordisk) Chemical_Formula
C1972H3076N560O597S28
NovoSeven (Novo Nordisk) RX_link
http://www.rxlist.com/cgi/generic3/novoseven.htm
NovoSeven (Novo Nordisk) fda sheet
NovoSeven (Novo Nordisk) msds (material safety sheet)
NovoSeven (Novo Nordisk) Synthesis Reference
No information avaliable
NovoSeven (Novo Nordisk) Molecular Weight
45079.1
NovoSeven (Novo Nordisk) Melting Point
58 oC (Petersen, L.C. et al., Eur. J. Biochem 261: 124-129 (1999)).
NovoSeven (Novo Nordisk) H2O Solubility
No information avaliable
NovoSeven (Novo Nordisk) State
Liquid
NovoSeven (Novo Nordisk) LogP
-0.311
NovoSeven (Novo Nordisk) Dosage Forms
Solution (IV injection); Solution (IV infusion); Tablet; Powder for solution
NovoSeven (Novo Nordisk) Indication
For treatment of hemorrhagic complications in hemophilia A and B
NovoSeven (Novo Nordisk) Pharmacology
Used in the treatment of bleeding episodes in hemophilia A or B. NovoSeven is recombinant Factor VIIa and, when complexed with tissue factor can activate coagulation Factor X to Factor Xa, as well as coagulation Factor IX to Factor IXa. Factor Xa, in complex with other factors, then converts prothrombin to thrombin, which leads to the formation of a hemostatic plug by converting fibrinogen to fibrin and thereby inducing local clotting.
NovoSeven (Novo Nordisk) Absorption
No information avaliable
NovoSeven (Novo Nordisk) side effects and Toxicity
No information avaliable
NovoSeven (Novo Nordisk) Patient Information
No information avaliable
NovoSeven (Novo Nordisk) Organisms Affected
Humans and other mammals
