Eptacog alfa
Brand names,
Eptacog alfa
Analogs
Eptacog alfa
Brand Names Mixture
Eptacog alfa
Chemical_Formula
C1972H3076N560O597S28
Eptacog alfa
RX_link
http://www.rxlist.com/cgi/generic3/novoseven.htm
Eptacog alfa
fda sheet
Eptacog alfa
msds (material safety sheet)
Eptacog alfa
Synthesis Reference
No information avaliable
Eptacog alfa
Molecular Weight
45079.1
Eptacog alfa
Melting Point
58 oC (Petersen, L.C. et al., Eur. J. Biochem 261: 124-129 (1999)).
Eptacog alfa
H2O Solubility
No information avaliable
Eptacog alfa
State
Liquid
Eptacog alfa
LogP
-0.311
Eptacog alfa
Dosage Forms
Solution (IV injection); Solution (IV infusion); Tablet; Powder for solution
Eptacog alfa
Indication
For treatment of hemorrhagic complications in hemophilia A and B
Eptacog alfa
Pharmacology
Used in the treatment of bleeding episodes in hemophilia A or B. NovoSeven is recombinant Factor VIIa and, when complexed with tissue factor can activate coagulation Factor X to Factor Xa, as well as coagulation Factor IX to Factor IXa. Factor Xa, in complex with other factors, then converts prothrombin to thrombin, which leads to the formation of a hemostatic plug by converting fibrinogen to fibrin and thereby inducing local clotting.
Eptacog alfa
Absorption
No information avaliable
Eptacog alfa
side effects and Toxicity
No information avaliable
Eptacog alfa
Patient Information
No information avaliable
Eptacog alfa
Organisms Affected
Humans and other mammals