Coagulation factor VII precursor
Brand names,
Coagulation factor VII precursor
Analogs
Coagulation factor VII precursor
Brand Names Mixture
Coagulation factor VII precursor
Chemical_Formula
C1972H3076N560O597S28
Coagulation factor VII precursor
RX_link
http://www.rxlist.com/cgi/generic3/novoseven.htm
Coagulation factor VII precursor
fda sheet
Coagulation factor VII precursor
msds (material safety sheet)
Coagulation factor VII precursor
Synthesis Reference
No information avaliable
Coagulation factor VII precursor
Molecular Weight
45079.1
Coagulation factor VII precursor
Melting Point
58 oC (Petersen, L.C. et al., Eur. J. Biochem 261: 124-129 (1999)).
Coagulation factor VII precursor
H2O Solubility
No information avaliable
Coagulation factor VII precursor
State
Liquid
Coagulation factor VII precursor
LogP
-0.311
Coagulation factor VII precursor
Dosage Forms
Solution (IV injection); Solution (IV infusion); Tablet; Powder for solution
Coagulation factor VII precursor
Indication
For treatment of hemorrhagic complications in hemophilia A and B
Coagulation factor VII precursor
Pharmacology
Used in the treatment of bleeding episodes in hemophilia A or B. NovoSeven is recombinant Factor VIIa and, when complexed with tissue factor can activate coagulation Factor X to Factor Xa, as well as coagulation Factor IX to Factor IXa. Factor Xa, in complex with other factors, then converts prothrombin to thrombin, which leads to the formation of a hemostatic plug by converting fibrinogen to fibrin and thereby inducing local clotting.
Coagulation factor VII precursor
Absorption
No information avaliable
Coagulation factor VII precursor
side effects and Toxicity
No information avaliable
Coagulation factor VII precursor
Patient Information
No information avaliable
Coagulation factor VII precursor
Organisms Affected
Humans and other mammals