SPCA
Brand names,
SPCA
Analogs
SPCA
Brand Names Mixture
SPCA
Chemical_Formula
C1972H3076N560O597S28
SPCA
RX_link
http://www.rxlist.com/cgi/generic3/novoseven.htm
SPCA
fda sheet
SPCA
msds (material safety sheet)
SPCA
Synthesis Reference
No information avaliable
SPCA
Molecular Weight
45079.1
SPCA
Melting Point
58 oC (Petersen, L.C. et al., Eur. J. Biochem 261: 124-129 (1999)).
SPCA
H2O Solubility
No information avaliable
SPCA
State
Liquid
SPCA
LogP
-0.311
SPCA
Dosage Forms
Solution (IV injection); Solution (IV infusion); Tablet; Powder for solution
SPCA
Indication
For treatment of hemorrhagic complications in hemophilia A and B
SPCA
Pharmacology
Used in the treatment of bleeding episodes in hemophilia A or B. NovoSeven is recombinant Factor VIIa and, when complexed with tissue factor can activate coagulation Factor X to Factor Xa, as well as coagulation Factor IX to Factor IXa. Factor Xa, in complex with other factors, then converts prothrombin to thrombin, which leads to the formation of a hemostatic plug by converting fibrinogen to fibrin and thereby inducing local clotting.
SPCA
Absorption
No information avaliable
SPCA
side effects and Toxicity
No information avaliable
SPCA
Patient Information
No information avaliable
SPCA
Organisms Affected
Humans and other mammals