Norvir Sec en es it fr

Norvir Sec Brand names, Norvir Sec Analogs

Norvir Sec Brand Names Mixture

  • Kaletra (Lopinavir + Ritonavir)

Norvir Sec Chemical_Formula


Norvir Sec RX_link

Norvir Sec fda sheet

Norvir_Sec FDA

Norvir Sec msds (material safety sheet)

Norvir_Sec MSDS

Norvir Sec Synthesis Reference

No information avaliable

Norvir Sec Molecular Weight

720.946 g/mol

Norvir Sec Melting Point

No information avaliable

Norvir Sec H2O Solubility

Practically insoluble

Norvir Sec State


Norvir Sec LogP


Norvir Sec Dosage Forms

Capsule (100 mg); Solution (80 mg/mL of ritonavir)

Norvir Sec Indication

Indicated in combination with other antiretroviral agents for the treatment of HIV-infection.

Norvir Sec Pharmacology

Ritonavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Ritonavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs.

Norvir Sec Absorption

The absolute bioavailability of ritonavir has not been determined.

Norvir Sec side effects and Toxicity

Human experience of acute overdose with NORVIR is limited. One patient in clinical trials took NORVIR 1500 mg/day for two days. The patient reported paresthesias which resolved after the dose was decreased. A post-marketing case of renal failure with eosinophilia has been reported with ritonavir overdose. The approximate lethal dose was found to be greater than 20 times the related human dose in rats and 10 times the related human dose in mice.

Norvir Sec Patient Information

No information avaliable

Norvir Sec Organisms Affected

Human immunodeficiency virus