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Norvir Brand names, Norvir Analogs

Norvir Brand Names Mixture

  • Kaletra (Lopinavir + Ritonavir)

Norvir Chemical_Formula


Norvir RX_link

Norvir fda sheet

Norvir FDA

Norvir msds (material safety sheet)

Norvir MSDS

Norvir Synthesis Reference

No information avaliable

Norvir Molecular Weight

720.946 g/mol

Norvir Melting Point

No information avaliable

Norvir H2O Solubility

Practically insoluble

Norvir State


Norvir LogP


Norvir Dosage Forms

Capsule (100 mg); Solution (80 mg/mL of ritonavir)

Norvir Indication

Indicated in combination with other antiretroviral agents for the treatment of HIV-infection.

Norvir Pharmacology

Ritonavir is a protease inhibitor with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Protease inhibitors block the part of HIV called protease. HIV-1 protease is an enzyme required for the proteolytic cleavage of the viral polyprotein precursors into the individual functional proteins found in infectious HIV-1. Ritonavir binds to the protease active site and inhibits the activity of the enzyme. This inhibition prevents cleavage of the viral polyproteins resulting in the formation of immature non-infectious viral particles. Protease inhibitors are almost always used in combination with at least two other anti-HIV drugs.

Norvir Absorption

The absolute bioavailability of ritonavir has not been determined.

Norvir side effects and Toxicity

Human experience of acute overdose with NORVIR is limited. One patient in clinical trials took NORVIR 1500 mg/day for two days. The patient reported paresthesias which resolved after the dose was decreased. A post-marketing case of renal failure with eosinophilia has been reported with ritonavir overdose. The approximate lethal dose was found to be greater than 20 times the related human dose in rats and 10 times the related human dose in mice.

Norvir Patient Information

No information avaliable

Norvir Organisms Affected

Human immunodeficiency virus