N-Methyloxazepam
Brand names,
N-Methyloxazepam
Analogs
N-Methyloxazepam
Brand Names Mixture
N-Methyloxazepam
Chemical_Formula
C16H13ClN2O2
N-Methyloxazepam
RX_link
http://www.rxlist.com/cgi/generic/temaz.htm
N-Methyloxazepam
fda sheet
N-Methyloxazepam
msds (material safety sheet)
N-Methyloxazepam
Synthesis Reference
E. Reeder et al., U.S. Pat. 3,340,253 (1967)
N-Methyloxazepam
Molecular Weight
300.739 g/mol
N-Methyloxazepam
Melting Point
119-121oC
N-Methyloxazepam
H2O Solubility
164 mg/L
N-Methyloxazepam
State
Solid
N-Methyloxazepam
LogP
2.479
N-Methyloxazepam
Dosage Forms
Capsule (7.5 mg, 15 mg, and 30 mg)
N-Methyloxazepam
Indication
For the short-term treatment of insomnia (generally 7-10 days).
N-Methyloxazepam
Pharmacology
Temazepam is a benzodiazepine used as a hypnotic agent in the management of insomnia. Temazepam produces CNS depression at limbic, thalamic, and hypothalamic levels of the CNS. Temazepam increases the affinity of the neurotransmitter gamma-aminobutyric acid (GABA) for GABA receptors by binding to benzodiazepine receptors. Results are sedation, hypnosis, skeletal muscle relaxation, anticonvulsant activity, and anxiolytic action.
N-Methyloxazepam
Absorption
Well absorbed, minimal first-pass metabolism.
N-Methyloxazepam
side effects and Toxicity
No information avaliable
N-Methyloxazepam
Patient Information
N-Methyloxazepam
Organisms Affected
Humans and other mammals