Signopam
Brand names,
Signopam
Analogs
Signopam
Brand Names Mixture
Signopam
Chemical_Formula
C16H13ClN2O2
Signopam
RX_link
http://www.rxlist.com/cgi/generic/temaz.htm
Signopam
fda sheet
Signopam
msds (material safety sheet)
Signopam
Synthesis Reference
E. Reeder et al., U.S. Pat. 3,340,253 (1967)
Signopam
Molecular Weight
300.739 g/mol
Signopam
Melting Point
119-121oC
Signopam
H2O Solubility
164 mg/L
Signopam
State
Solid
Signopam
LogP
2.479
Signopam
Dosage Forms
Capsule (7.5 mg, 15 mg, and 30 mg)
Signopam
Indication
For the short-term treatment of insomnia (generally 7-10 days).
Signopam
Pharmacology
Temazepam is a benzodiazepine used as a hypnotic agent in the management of insomnia. Temazepam produces CNS depression at limbic, thalamic, and hypothalamic levels of the CNS. Temazepam increases the affinity of the neurotransmitter gamma-aminobutyric acid (GABA) for GABA receptors by binding to benzodiazepine receptors. Results are sedation, hypnosis, skeletal muscle relaxation, anticonvulsant activity, and anxiolytic action.
Signopam
Absorption
Well absorbed, minimal first-pass metabolism.
Signopam
side effects and Toxicity
No information avaliable
Signopam
Patient Information
Signopam
Organisms Affected
Humans and other mammals