Hydroxydiazepam
Brand names,
Hydroxydiazepam
Analogs
Hydroxydiazepam
Brand Names Mixture
Hydroxydiazepam
Chemical_Formula
C16H13ClN2O2
Hydroxydiazepam
RX_link
http://www.rxlist.com/cgi/generic/temaz.htm
Hydroxydiazepam
fda sheet
Hydroxydiazepam
msds (material safety sheet)
Hydroxydiazepam
Synthesis Reference
E. Reeder et al., U.S. Pat. 3,340,253 (1967)
Hydroxydiazepam
Molecular Weight
300.739 g/mol
Hydroxydiazepam
Melting Point
119-121oC
Hydroxydiazepam
H2O Solubility
164 mg/L
Hydroxydiazepam
State
Solid
Hydroxydiazepam
LogP
2.479
Hydroxydiazepam
Dosage Forms
Capsule (7.5 mg, 15 mg, and 30 mg)
Hydroxydiazepam
Indication
For the short-term treatment of insomnia (generally 7-10 days).
Hydroxydiazepam
Pharmacology
Temazepam is a benzodiazepine used as a hypnotic agent in the management of insomnia. Temazepam produces CNS depression at limbic, thalamic, and hypothalamic levels of the CNS. Temazepam increases the affinity of the neurotransmitter gamma-aminobutyric acid (GABA) for GABA receptors by binding to benzodiazepine receptors. Results are sedation, hypnosis, skeletal muscle relaxation, anticonvulsant activity, and anxiolytic action.
Hydroxydiazepam
Absorption
Well absorbed, minimal first-pass metabolism.
Hydroxydiazepam
side effects and Toxicity
No information avaliable
Hydroxydiazepam
Patient Information
Hydroxydiazepam
Organisms Affected
Humans and other mammals