Modafinil
Brand names,
Modafinil
Analogs
Modafinil
Brand Names Mixture
Modafinil
Chemical_Formula
C15H15NO2S
Modafinil
RX_link
http://www.rxlist.com/cgi/generic2/modafinil.htm
Modafinil
fda sheet
Modafinil
msds (material safety sheet)
Modafinil
Synthesis Reference
L. Lafon, U.S. pat. 4,927,855, (1990)
Modafinil
Molecular Weight
273.351 g/mol
Modafinil
Melting Point
164-166 oC
Modafinil
H2O Solubility
Slightly soluble
Modafinil
State
Solid
Modafinil
LogP
1.736
Modafinil
Dosage Forms
Tablet
Modafinil
Indication
To improve wakefulness in patients with excessive daytime sleepiness (EDS) associated with narcolepsy.
Modafinil
Pharmacology
Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. The prexin neuron activation is associated with psychoactivation and euphoria. Modafinil is not indicated for complaints of lack of energy or fatigue; but it appears to be very helpful for some patients. Also, it has been used in the treatment of hypersomnia, a disorder in which patients lack the capacity for meaningful sleep and may require ten or more hours per day. Recent studies have have found that modafinil may help recovering cocaine addicts fight their addiction.
Modafinil
Absorption
Rapid following oral administration.
Modafinil
side effects and Toxicity
No information avaliable
Modafinil
Patient Information
Modafinil
Organisms Affected
Humans and other mammals