Provigil
Brand names,
Provigil
Analogs
Provigil
Brand Names Mixture
Provigil
Chemical_Formula
C15H15NO2S
Provigil
RX_link
http://www.rxlist.com/cgi/generic2/modafinil.htm
Provigil
fda sheet
Provigil
msds (material safety sheet)
Provigil
Synthesis Reference
L. Lafon, U.S. pat. 4,927,855, (1990)
Provigil
Molecular Weight
273.351 g/mol
Provigil
Melting Point
164-166 oC
Provigil
H2O Solubility
Slightly soluble
Provigil
State
Solid
Provigil
LogP
1.736
Provigil
Dosage Forms
Tablet
Provigil
Indication
To improve wakefulness in patients with excessive daytime sleepiness (EDS) associated with narcolepsy.
Provigil
Pharmacology
Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. The prexin neuron activation is associated with psychoactivation and euphoria. Modafinil is not indicated for complaints of lack of energy or fatigue; but it appears to be very helpful for some patients. Also, it has been used in the treatment of hypersomnia, a disorder in which patients lack the capacity for meaningful sleep and may require ten or more hours per day. Recent studies have have found that modafinil may help recovering cocaine addicts fight their addiction.
Provigil
Absorption
Rapid following oral administration.
Provigil
side effects and Toxicity
No information avaliable
Provigil
Patient Information
Provigil
Organisms Affected
Humans and other mammals