Modiodal
Brand names,
Modiodal
Analogs
Modiodal
Brand Names Mixture
Modiodal
Chemical_Formula
C15H15NO2S
Modiodal
RX_link
http://www.rxlist.com/cgi/generic2/modafinil.htm
Modiodal
fda sheet
Modiodal
msds (material safety sheet)
Modiodal
Synthesis Reference
L. Lafon, U.S. pat. 4,927,855, (1990)
Modiodal
Molecular Weight
273.351 g/mol
Modiodal
Melting Point
164-166 oC
Modiodal
H2O Solubility
Slightly soluble
Modiodal
State
Solid
Modiodal
LogP
1.736
Modiodal
Dosage Forms
Tablet
Modiodal
Indication
To improve wakefulness in patients with excessive daytime sleepiness (EDS) associated with narcolepsy.
Modiodal
Pharmacology
Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. The prexin neuron activation is associated with psychoactivation and euphoria. Modafinil is not indicated for complaints of lack of energy or fatigue; but it appears to be very helpful for some patients. Also, it has been used in the treatment of hypersomnia, a disorder in which patients lack the capacity for meaningful sleep and may require ten or more hours per day. Recent studies have have found that modafinil may help recovering cocaine addicts fight their addiction.
Modiodal
Absorption
Rapid following oral administration.
Modiodal
side effects and Toxicity
No information avaliable
Modiodal
Patient Information
Modiodal
Organisms Affected
Humans and other mammals