Moclobemide
Brand names,
Moclobemide
Analogs
Moclobemide
Brand Names Mixture
Moclobemide
Chemical_Formula
C13H17ClN2O2
Moclobemide
RX_link
No information avaliable
Moclobemide
fda sheet
Moclobemide
msds (material safety sheet)
Moclobemide
Synthesis Reference
No information avaliable
Moclobemide
Molecular Weight
268.739 g/mol
Moclobemide
Melting Point
No information avaliable
Moclobemide
H2O Solubility
No information avaliable
Moclobemide
State
Solid
Moclobemide
LogP
1.298
Moclobemide
Dosage Forms
Tablet
Moclobemide
Indication
For the treatment of depression.
Moclobemide
Pharmacology
Moclobemide belongs to a class of MAOI antidepressants known as reversible inhibitors of monoamine oxidase type-A (RIMAs). The primary role of monoamine oxidase MAO lies in the metabolism of and regulation of the levels of monoamines (serotonin, norepinephrine, and dopamine). Within neurons, MAO appears to regulate the levels of monoamines released upon synaptic firing. Since depression is associated with low levels of monoamines, the inhibition of MAO serves to ease depressive symptoms. RIMAs demonstrate transient inhibition of the substrate binding site of MAO-A as well as competitive displacement from this site by bioamines. The RIMAs are distinguished from the older monoamine oxidase inhibitors (MAOIs) by their selectivity and reversibility.
Moclobemide
Absorption
No information avaliable
Moclobemide
side effects and Toxicity
No information avaliable
Moclobemide
Patient Information
No information avaliable
Moclobemide
Organisms Affected
Humans and other mammals