Moclobemid
Brand names,
Moclobemid
Analogs
Moclobemid
Brand Names Mixture
Moclobemid
Chemical_Formula
C13H17ClN2O2
Moclobemid
RX_link
No information avaliable
Moclobemid
fda sheet
Moclobemid
msds (material safety sheet)
Moclobemid
Synthesis Reference
No information avaliable
Moclobemid
Molecular Weight
268.739 g/mol
Moclobemid
Melting Point
No information avaliable
Moclobemid
H2O Solubility
No information avaliable
Moclobemid
State
Solid
Moclobemid
LogP
1.298
Moclobemid
Dosage Forms
Tablet
Moclobemid
Indication
For the treatment of depression.
Moclobemid
Pharmacology
Moclobemide belongs to a class of MAOI antidepressants known as reversible inhibitors of monoamine oxidase type-A (RIMAs). The primary role of monoamine oxidase MAO lies in the metabolism of and regulation of the levels of monoamines (serotonin, norepinephrine, and dopamine). Within neurons, MAO appears to regulate the levels of monoamines released upon synaptic firing. Since depression is associated with low levels of monoamines, the inhibition of MAO serves to ease depressive symptoms. RIMAs demonstrate transient inhibition of the substrate binding site of MAO-A as well as competitive displacement from this site by bioamines. The RIMAs are distinguished from the older monoamine oxidase inhibitors (MAOIs) by their selectivity and reversibility.
Moclobemid
Absorption
No information avaliable
Moclobemid
side effects and Toxicity
No information avaliable
Moclobemid
Patient Information
No information avaliable
Moclobemid
Organisms Affected
Humans and other mammals