Moclamide
Brand names,
Moclamide
Analogs
Moclamide
Brand Names Mixture
Moclamide
Chemical_Formula
C13H17ClN2O2
Moclamide
RX_link
No information avaliable
Moclamide
fda sheet
Moclamide
msds (material safety sheet)
Moclamide
Synthesis Reference
No information avaliable
Moclamide
Molecular Weight
268.739 g/mol
Moclamide
Melting Point
No information avaliable
Moclamide
H2O Solubility
No information avaliable
Moclamide
State
Solid
Moclamide
LogP
1.298
Moclamide
Dosage Forms
Tablet
Moclamide
Indication
For the treatment of depression.
Moclamide
Pharmacology
Moclobemide belongs to a class of MAOI antidepressants known as reversible inhibitors of monoamine oxidase type-A (RIMAs). The primary role of monoamine oxidase MAO lies in the metabolism of and regulation of the levels of monoamines (serotonin, norepinephrine, and dopamine). Within neurons, MAO appears to regulate the levels of monoamines released upon synaptic firing. Since depression is associated with low levels of monoamines, the inhibition of MAO serves to ease depressive symptoms. RIMAs demonstrate transient inhibition of the substrate binding site of MAO-A as well as competitive displacement from this site by bioamines. The RIMAs are distinguished from the older monoamine oxidase inhibitors (MAOIs) by their selectivity and reversibility.
Moclamide
Absorption
No information avaliable
Moclamide
side effects and Toxicity
No information avaliable
Moclamide
Patient Information
No information avaliable
Moclamide
Organisms Affected
Humans and other mammals