Manerix
Brand names,
Manerix
Analogs
Manerix
Brand Names Mixture
Manerix
Chemical_Formula
C13H17ClN2O2
Manerix
RX_link
No information avaliable
Manerix
fda sheet
Manerix
msds (material safety sheet)
Manerix
Synthesis Reference
No information avaliable
Manerix
Molecular Weight
268.739 g/mol
Manerix
Melting Point
No information avaliable
Manerix
H2O Solubility
No information avaliable
Manerix
State
Solid
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LogP
1.298
Manerix
Dosage Forms
Tablet
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Indication
For the treatment of depression.
Manerix
Pharmacology
Moclobemide belongs to a class of MAOI antidepressants known as reversible inhibitors of monoamine oxidase type-A (RIMAs). The primary role of monoamine oxidase MAO lies in the metabolism of and regulation of the levels of monoamines (serotonin, norepinephrine, and dopamine). Within neurons, MAO appears to regulate the levels of monoamines released upon synaptic firing. Since depression is associated with low levels of monoamines, the inhibition of MAO serves to ease depressive symptoms. RIMAs demonstrate transient inhibition of the substrate binding site of MAO-A as well as competitive displacement from this site by bioamines. The RIMAs are distinguished from the older monoamine oxidase inhibitors (MAOIs) by their selectivity and reversibility.
Manerix
Absorption
No information avaliable
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side effects and Toxicity
No information avaliable
Manerix
Patient Information
No information avaliable
Manerix
Organisms Affected
Humans and other mammals