Miconazole
Miconazole Brand names, Miconazole Analogs
Miconazole Brand Names Mixture
- No information avaliable
Miconazole Chemical_Formula
C18H14Cl4N2O
Miconazole RX_link
http://www.rxlist.com/cgi/generic2/micon.htm
Miconazole fda sheet
Miconazole msds (material safety sheet)
Miconazole Synthesis Reference
No information avaliable
Miconazole Molecular Weight
416.127 g/mol
Miconazole Melting Point
159 - 163 oC
Miconazole H2O Solubility
1g/100mL (20°C)
Miconazole State
Solid
Miconazole LogP
6.02
Miconazole Dosage Forms
Topical cream (2%); Vaginal cream (2%); Vaginal suppositories (100mg, 200mg)
Miconazole Indication
For topical application in the treatment of tinea pedis (athlete’s foot), tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis (moniliasis), and in the treatment of tinea versicolor.
Miconazole Pharmacology
Miconazole is an anti-fungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). It is used either on the skin or in the vagina for fungal infections. Miconazole was approved by the FDA in 1974. Miconazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Miconazole Absorption
No information avaliable
Miconazole side effects and Toxicity
Oral, mouse: LD50 = 3800 mg/kg; Oral, rat: LD50 = 3 gm/kg. Ingestion of the amounts of the components contained in a tube of cream are unlikely to produce overdosage and toxic effects.
Miconazole Patient Information
No information avaliable
Miconazole Organisms Affected
Fungi, yeast and protozoans
