Mykrox
Brand names,
Mykrox
Analogs
Mykrox
Brand Names Mixture
Mykrox
Chemical_Formula
C18H14Cl4N2O
Mykrox
RX_link
http://www.rxlist.com/cgi/generic2/micon.htm
Mykrox
fda sheet
Mykrox
msds (material safety sheet)
Mykrox
Synthesis Reference
No information avaliable
Mykrox
Molecular Weight
416.127 g/mol
Mykrox
Melting Point
159 - 163 oC
Mykrox
H2O Solubility
1g/100mL (20°C)
Mykrox
State
Solid
Mykrox
LogP
6.02
Mykrox
Dosage Forms
Topical cream (2%); Vaginal cream (2%); Vaginal suppositories (100mg, 200mg)
Mykrox
Indication
For topical application in the treatment of tinea pedis (athlete’s foot), tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis (moniliasis), and in the treatment of tinea versicolor.
Mykrox
Pharmacology
Miconazole is an anti-fungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). It is used either on the skin or in the vagina for fungal infections. Miconazole was approved by the FDA in 1974. Miconazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Mykrox
Absorption
No information avaliable
Mykrox
side effects and Toxicity
Oral, mouse: LD50 = 3800 mg/kg; Oral, rat: LD50 = 3 gm/kg. Ingestion of the amounts of the components contained in a tube of cream are unlikely to produce overdosage and toxic effects.
Mykrox
Patient Information
No information avaliable
Mykrox
Organisms Affected
Fungi, yeast and protozoans