Zaroxolyn
Brand names,
Zaroxolyn
Analogs
Zaroxolyn
Brand Names Mixture
Zaroxolyn
Chemical_Formula
C18H14Cl4N2O
Zaroxolyn
RX_link
http://www.rxlist.com/cgi/generic2/micon.htm
Zaroxolyn
fda sheet
Zaroxolyn
msds (material safety sheet)
Zaroxolyn
Synthesis Reference
No information avaliable
Zaroxolyn
Molecular Weight
416.127 g/mol
Zaroxolyn
Melting Point
159 - 163 oC
Zaroxolyn
H2O Solubility
1g/100mL (20°C)
Zaroxolyn
State
Solid
Zaroxolyn
LogP
6.02
Zaroxolyn
Dosage Forms
Topical cream (2%); Vaginal cream (2%); Vaginal suppositories (100mg, 200mg)
Zaroxolyn
Indication
For topical application in the treatment of tinea pedis (athlete’s foot), tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis (moniliasis), and in the treatment of tinea versicolor.
Zaroxolyn
Pharmacology
Miconazole is an anti-fungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). It is used either on the skin or in the vagina for fungal infections. Miconazole was approved by the FDA in 1974. Miconazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Zaroxolyn
Absorption
No information avaliable
Zaroxolyn
side effects and Toxicity
Oral, mouse: LD50 = 3800 mg/kg; Oral, rat: LD50 = 3 gm/kg. Ingestion of the amounts of the components contained in a tube of cream are unlikely to produce overdosage and toxic effects.
Zaroxolyn
Patient Information
No information avaliable
Zaroxolyn
Organisms Affected
Fungi, yeast and protozoans