Metalazone
Metalazone Brand names, Metalazone Analogs
Metalazone Brand Names Mixture
- No information avaliable
Metalazone Chemical_Formula
C18H14Cl4N2O
Metalazone RX_link
http://www.rxlist.com/cgi/generic2/micon.htm
Metalazone fda sheet
Metalazone msds (material safety sheet)
Metalazone Synthesis Reference
No information avaliable
Metalazone Molecular Weight
416.127 g/mol
Metalazone Melting Point
159 - 163 oC
Metalazone H2O Solubility
1g/100mL (20°C)
Metalazone State
Solid
Metalazone LogP
6.02
Metalazone Dosage Forms
Topical cream (2%); Vaginal cream (2%); Vaginal suppositories (100mg, 200mg)
Metalazone Indication
For topical application in the treatment of tinea pedis (athlete’s foot), tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis (moniliasis), and in the treatment of tinea versicolor.
Metalazone Pharmacology
Miconazole is an anti-fungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). It is used either on the skin or in the vagina for fungal infections. Miconazole was approved by the FDA in 1974. Miconazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.
Metalazone Absorption
No information avaliable
Metalazone side effects and Toxicity
Oral, mouse: LD50 = 3800 mg/kg; Oral, rat: LD50 = 3 gm/kg. Ingestion of the amounts of the components contained in a tube of cream are unlikely to produce overdosage and toxic effects.
Metalazone Patient Information
No information avaliable
Metalazone Organisms Affected
Fungi, yeast and protozoans
