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Metocurini Iodidum Brand names, Metocurini Iodidum Analogs

Metocurini Iodidum Brand Names Mixture

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Metocurini Iodidum Chemical_Formula


Metocurini Iodidum RX_link

Metocurini Iodidum fda sheet

Metocurini_Iodidum FDA

Metocurini Iodidum msds (material safety sheet)

Metocurini Iodidum Synthesis Reference

No information avaliable

Metocurini Iodidum Molecular Weight

469.955 g/mol

Metocurini Iodidum Melting Point

No information avaliable

Metocurini Iodidum H2O Solubility

Slightly soluble (43 mg/mL at pH 7.4)

Metocurini Iodidum State


Metocurini Iodidum LogP


Metocurini Iodidum Dosage Forms

Capsule (250mg); Tablet (500 mg); Powder for solution (200 mg/mL constituted)

Metocurini Iodidum Indication

For the prophylaxis of organ rejection in patients receiving allogeneic renal, cardiac or hepatic transplants. CellCept should be used concomitantly with cyclosporine and corticosteroids.

Metocurini Iodidum Pharmacology

Mycophenolate mofetil is a prodrug of mycophenolic acid, an antibiotic substance derived from Penicillium stoloniferum. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase. Mycophenolic acid is important because of its selective effects on the immune system. It prevents the proliferation of T-cells, lymphocytes, and the formation of antibodies from B-cells. It also may inhibit recruitment of leukocytes to inflammatory sites.

Metocurini Iodidum Absorption

Rapidly absorbed following oral administration. In 12 healthy volunteers, the mean absolute bioavailability of oral mycophenolate mofetil relative to intravenous mycophenolate mofetil (based on MPA AUC) was 94%. Food (27 g fat, 650 calories) has no effect on the extent of absorption (MPA AUC) of mycophenolate mofetil.

Metocurini Iodidum side effects and Toxicity

Oral (LD50): Acute: 352 mg/kg [Rat], 1000 mg/kg [Mouse], and >6000 mg/kg [Rabbit]. Possible signs and symptoms of acute overdose could include the following: hematological abnormalities such as leukopenia and neutropenia, and gastrointestinal symptoms such as abdominal pain, diarrhea, nausea and vomiting, and dyspepsia.

Metocurini Iodidum Patient Information

No information avaliable

Metocurini Iodidum Organisms Affected

Humans and other mammals