Dimetiltubocurarinio, ioduro de en es it fr

Dimetiltubocurarinio, ioduro de Brand names, Dimetiltubocurarinio, ioduro de Analogs

Dimetiltubocurarinio, ioduro de Brand Names Mixture

  • No information avaliable

Dimetiltubocurarinio, ioduro de Chemical_Formula

C23H31NO7

Dimetiltubocurarinio, ioduro de RX_link

http://www.rxlist.com/cgi/generic3/cellcept.htm

Dimetiltubocurarinio, ioduro de fda sheet

Dimetiltubocurarinio,_ioduro_de FDA

Dimetiltubocurarinio, ioduro de msds (material safety sheet)

Dimetiltubocurarinio, ioduro de Synthesis Reference

No information avaliable

Dimetiltubocurarinio, ioduro de Molecular Weight

469.955 g/mol

Dimetiltubocurarinio, ioduro de Melting Point

No information avaliable

Dimetiltubocurarinio, ioduro de H2O Solubility

Slightly soluble (43 mg/mL at pH 7.4)

Dimetiltubocurarinio, ioduro de State

Solid

Dimetiltubocurarinio, ioduro de LogP

2.424

Dimetiltubocurarinio, ioduro de Dosage Forms

Capsule (250mg); Tablet (500 mg); Powder for solution (200 mg/mL constituted)

Dimetiltubocurarinio, ioduro de Indication

For the prophylaxis of organ rejection in patients receiving allogeneic renal, cardiac or hepatic transplants. CellCept should be used concomitantly with cyclosporine and corticosteroids.

Dimetiltubocurarinio, ioduro de Pharmacology

Mycophenolate mofetil is a prodrug of mycophenolic acid, an antibiotic substance derived from Penicillium stoloniferum. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase. Mycophenolic acid is important because of its selective effects on the immune system. It prevents the proliferation of T-cells, lymphocytes, and the formation of antibodies from B-cells. It also may inhibit recruitment of leukocytes to inflammatory sites.

Dimetiltubocurarinio, ioduro de Absorption

Rapidly absorbed following oral administration. In 12 healthy volunteers, the mean absolute bioavailability of oral mycophenolate mofetil relative to intravenous mycophenolate mofetil (based on MPA AUC) was 94%. Food (27 g fat, 650 calories) has no effect on the extent of absorption (MPA AUC) of mycophenolate mofetil.

Dimetiltubocurarinio, ioduro de side effects and Toxicity

Oral (LD50): Acute: 352 mg/kg [Rat], 1000 mg/kg [Mouse], and >6000 mg/kg [Rabbit]. Possible signs and symptoms of acute overdose could include the following: hematological abnormalities such as leukopenia and neutropenia, and gastrointestinal symptoms such as abdominal pain, diarrhea, nausea and vomiting, and dyspepsia.

Dimetiltubocurarinio, ioduro de Patient Information

No information avaliable

Dimetiltubocurarinio, ioduro de Organisms Affected

Humans and other mammals