Dimethyl Tubocurarine Iodide
Dimethyl Tubocurarine Iodide Brand names, Dimethyl Tubocurarine Iodide Analogs
Dimethyl Tubocurarine Iodide Brand Names Mixture
- No information avaliable
Dimethyl Tubocurarine Iodide Chemical_Formula
C23H31NO7
Dimethyl Tubocurarine Iodide RX_link
http://www.rxlist.com/cgi/generic3/cellcept.htm
Dimethyl Tubocurarine Iodide fda sheet
Dimethyl Tubocurarine Iodide msds (material safety sheet)
Dimethyl Tubocurarine Iodide Synthesis Reference
No information avaliable
Dimethyl Tubocurarine Iodide Molecular Weight
469.955 g/mol
Dimethyl Tubocurarine Iodide Melting Point
No information avaliable
Dimethyl Tubocurarine Iodide H2O Solubility
Slightly soluble (43 mg/mL at pH 7.4)
Dimethyl Tubocurarine Iodide State
Solid
Dimethyl Tubocurarine Iodide LogP
2.424
Dimethyl Tubocurarine Iodide Dosage Forms
Capsule (250mg); Tablet (500 mg); Powder for solution (200 mg/mL constituted)
Dimethyl Tubocurarine Iodide Indication
For the prophylaxis of organ rejection in patients receiving allogeneic renal, cardiac or hepatic transplants. CellCept should be used concomitantly with cyclosporine and corticosteroids.
Dimethyl Tubocurarine Iodide Pharmacology
Mycophenolate mofetil is a prodrug of mycophenolic acid, an antibiotic substance derived from Penicillium stoloniferum. It blocks de novo biosynthesis of purine nucleotides by inhibition of the enzyme inosine monophosphate dehydrogenase. Mycophenolic acid is important because of its selective effects on the immune system. It prevents the proliferation of T-cells, lymphocytes, and the formation of antibodies from B-cells. It also may inhibit recruitment of leukocytes to inflammatory sites.
Dimethyl Tubocurarine Iodide Absorption
Rapidly absorbed following oral administration. In 12 healthy volunteers, the mean absolute bioavailability of oral mycophenolate mofetil relative to intravenous mycophenolate mofetil (based on MPA AUC) was 94%. Food (27 g fat, 650 calories) has no effect on the extent of absorption (MPA AUC) of mycophenolate mofetil.
Dimethyl Tubocurarine Iodide side effects and Toxicity
Oral (LD50): Acute: 352 mg/kg [Rat], 1000 mg/kg [Mouse], and >6000 mg/kg [Rabbit]. Possible signs and symptoms of acute overdose could include the following: hematological abnormalities such as leukopenia and neutropenia, and gastrointestinal symptoms such as abdominal pain, diarrhea, nausea and vomiting, and dyspepsia.
Dimethyl Tubocurarine Iodide Patient Information
No information avaliable
Dimethyl Tubocurarine Iodide Organisms Affected
Humans and other mammals
