Methysergidum [INN-Latin]
Brand names,
Methysergidum [INN-Latin]
Analogs
Methysergidum [INN-Latin]
Brand Names Mixture
Methysergidum [INN-Latin]
Chemical_Formula
C21H27N3O2
Methysergidum [INN-Latin]
RX_link
http://www.rxlist.com/cgi/generic3/sansert.htm
Methysergidum [INN-Latin]
fda sheet
Methysergidum [INN-Latin]
msds (material safety sheet)
Methysergidum [INN-Latin]
Synthesis Reference
No information avaliable
Methysergidum [INN-Latin]
Molecular Weight
353.458 g/mol
Methysergidum [INN-Latin]
Melting Point
195 oC
Methysergidum [INN-Latin]
H2O Solubility
No information avaliable
Methysergidum [INN-Latin]
State
Solid
Methysergidum [INN-Latin]
LogP
1.55
Methysergidum [INN-Latin]
Dosage Forms
Tablet
Methysergidum [INN-Latin]
Indication
For the treatment of vascular headache
Methysergidum [INN-Latin]
Pharmacology
Methysergide has been shown, in vitro and in vivo, to inhibit or block the effects of serotonin, a substance which may be involved in the mechanism of vascular headaches. Serotonin has been variously described as a central neurohumoral agent or chemical mediator, as a "headache substance" acting directly or indirectly to lower pain threshold, as an intrinsic "motor hormone" of the gastrointestinal tract, and as a "hormone" involved in connective tissue reparative processes.
Methysergidum [INN-Latin]
Absorption
Rapid
Methysergidum [INN-Latin]
side effects and Toxicity
No information avaliable
Methysergidum [INN-Latin]
Patient Information
No information avaliable
Methysergidum [INN-Latin]
Organisms Affected
Humans and other mammals