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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C21H27N3O2
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RX_link
http://www.rxlist.com/cgi/generic3/sansert.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
353.458 g/mol
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Melting Point
195 oC
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H2O Solubility
No information avaliable
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State
Solid
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LogP
1.55
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Dosage Forms
Tablet
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Indication
For the treatment of vascular headache
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Pharmacology
Methysergide has been shown, in vitro and in vivo, to inhibit or block the effects of serotonin, a substance which may be involved in the mechanism of vascular headaches. Serotonin has been variously described as a central neurohumoral agent or chemical mediator, as a "headache substance" acting directly or indirectly to lower pain threshold, as an intrinsic "motor hormone" of the gastrointestinal tract, and as a "hormone" involved in connective tissue reparative processes.
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Absorption
Rapid
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side effects and Toxicity
No information avaliable
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals